Clinical trial intelligence · for CROs

Know your enrolment risk before it becomes your commitment.

Independent country and site intelligence behind your bid, with every assumption open to a sponsor's questions. Your feasibility lead sets the weights and owns the recommendation.

thehyvv.com/read/country-scope
Hyvv per-country site estimates expanded to named research centres
A country score, expanded to the named trial sites behind it
Sourced, dated and checkable, for whoever has to justify the decision later.
RANKED
Every country classed Recommended, Reserve or Avoid. Not a score on a 1 to 10 spectrum.
BENCHMARKED
Enrolment rates from comparable trials, not general market size.
CALIBRATED
Weights set to your indication and phase, shown line by line.
DATED
Every read timestamped, so it can be checked against later.
The problem

You commit to a number before you have the evidence.

Feasibility gets the shortest timeline and carries the longest consequence. Whatever goes into the proposal becomes the number you are measured against for the life of the study.

The window closes before the analysis does.

Country strategy gets built on whatever evidence fits inside the RFP window.

The bid number becomes the commitment.

The rate you propose is the rate you are measured against, and argued over in every change order.

The site list starts from delivery history.

Internal metrics show where sites performed on past studies. They cannot show which trials are competing for those patients now, or which investigators are already committed.

How a score is built

Six layers. Weighted by protocol.

Input

Study parameters

Indication, phase and eligibility criteria, with target enrolment and country scope where you have them. No protocol needed.

L1

Patient epidemiology

Are there enough eligible patients in this country?

Incidence and prevalence, narrowed to the population your eligibility criteria will actually admit.

L2

Competing trial density

How many of those patients are already committed elsewhere?

Trials recruiting the same population in the same market, weighted by how directly they overlap with yours.

L3

PI workload and availability

Do investigators here have room to take this on?

Investigator experience in this indication, and how much of their capacity is already committed.

L4

Site capability and readiness

Has this site run trials like yours before?

What a site has run before, in what phase and at what scale, so questionnaires go only to sites already worth asking.

L5

Regulatory environment

How long until a country can realistically open?

Approval pathways and submission timelines in each market, and what they mean for activation.

L6

Enrolment benchmark

What have comparable trials actually delivered here?

Median patients per site per month from comparable trials, labelled by how each country's rate was sourced.

Output

Country strategy and site list

Every country classed, every site named, every score open at each layer. Your analyst sets the weights by indication, phase and protocol requirement, and the reasoning stays visible all the way into the bid defence. Nothing collapses into a number you have to defend on faith.

The weighting

Every weight, shown line by line.

A Phase I oncology study is not scored like a Phase III cardiovascular trial. Your analysts set the weights and can show a sponsor exactly why, from a table rather than a spreadsheet nobody else can follow.

thehyvv.com/weights
Hyvv sub-weight controls, three weighted inputs summing to 100
Lock the weights that matter. The rest rebalance.
What's different

Built to survive being checked.

Point in time

Lock the analysis to the bid date, and when enrolment underruns you can show the sponsor a market that changed rather than an assumption that was wrong.

Independent

A separately sourced read that stands on its own evidence, which is what makes it worth putting in front of a sponsor.

Actionable

Every flagged risk carries a specific mitigation and a direction of travel, not a severity label with nothing attached to it.

thehyvv.com/read/comparable-trials
Hyvv reference trials list, by NCT identifier, phase and indication
The comparable trials behind a benchmark, by NCT ID
The evidence

Open any score down to the trials underneath it.

The layers, the weights, and every study behind them by NCT ID, from the competing trials counted against a country to the benchmark cohort behind its enrolment rate. Open the calculation in the room and argue from evidence, with each country classed rather than scored on a spectrum.

RECOMMENDED RESERVE AVOID
Enrolment

Commit to an enrolment rate you can defend.

Rates come from comparable trials: country-specific evidence where it exists, regional or global fallbacks where it does not.

Rate-source coverage
Country-specific Regional fallback Global fallback
Underneath the analysis

The same site, scattered across records that do not agree.

One clinical trial site turns up across registries, publications, regulatory submissions and site directories, commonly under a different name in each. Its investigators are recorded separately, its studies apart from both. Nothing is scored until Hyvv resolves which records match, so your analysts read evidence instead of reconciling it.

Public and licensed sources
Trials
Sites
Investigators
Protocols
Matched

Hyvv graph

One record per site, investigator and study.

Intelligence engine

Six layers, weighted to your protocol.

Country strategy and site list

Graph = the resolved data foundation.

Engine = the scoring system that reads it.

Behind your team, not instead of it

Fits inside how you already bid.

Your feasibility lead still owns the recommendation and the sponsor relationship. Hyvv gives them the evidence base and the working underneath it, so the judgement stays theirs and the reasoning holds up when it is questioned.

At RFP

Turn study parameters into a scored country and site view in 48 to 72 hours, so the bid team argues strategy instead of waiting on data.

In bid defence

Open the calculation in front of the sponsor: the comparable trials, the weights and the enrolment evidence behind the projection.

After award

An amendment, a dropped country, enrolment underrunning. Re-run the question without restarting the process.

No systems access No integration No change to your SOPs Your team owns the sponsor relationship You decide what the sponsor sees
Report or platform

Start with a report.

A report is a point-in-time read: every country classed Recommended, Reserve or Avoid, with the weights calibrated to your protocol and locked to that moment. It is fixed on purpose, so it can be checked and signed rather than moving underneath you.

Start here

The report

  • Every country classed Recommended, Reserve or Avoid, with named sites behind each one
  • Weights calibrated to your indication and phase, shown line by line
  • Enrolment benchmarks from comparable trials, labelled by source
  • Dated, so it can be checked against later
  • Live link and PDF, in seven working days
Later

The platform

  • Move the weights yourself and re-run in real time
  • Test a country plan against alternatives before you commit to one
  • Answer a sponsor's follow-up question in the meeting, rather than after it
  • A dedicated instance, configured for your team
How to start

Judge the method before it goes near a bid.

The protocol belongs to your sponsor. You do not have to hand it over to find out whether the method works.

1

Pick a study you delivered.

One of your own completed trials, or any public study.

All we need to run a first read
  • The indication and phase
  • Eligibility criteria in outline
  • Your target enrolment
  • The countries you are weighing up

All of it fits in a short conversation. Nothing leaves your organisation.

2

We run it and show the working.

Layer by layer, on a study where your team already knows how enrolment went.

3

Then a live bid.

If the read holds up against what you saw, we sign an NDA and work from a synopsis on a real RFP.

48 to 72 hours in a bid window

This first stage does not require

Your sponsor's protocol, until the right agreements are in place
Access to your CTMS, EDC or any internal system
Anything requiring a sponsor's permission before you could share it
An integration, a login, or anything IT has to set up

Priced per report, by indication and country scope, with volume terms for teams bidding regularly. No platform licence, no seat fees, no annual commitment.

Early partner programme

Run your own studies. Tell us where we are wrong.

We are refining the engine with a small group of CROs and sponsors who run their own analyses, compare our read against what they already know, and say where it holds and where it does not. Their judgement is what makes the next report better.

What you get

Access to run your own studies ahead of general release, with the working open at every layer and direct input on what gets built next.

What we ask

Your read on the output against a study you have already delivered. Where it matched what happened, and where it did not.

What it takes

One study to start and a short call to walk through the output. We run the analysis. Your side of it is the review.

We will send an example report, and details of the partner programme if it looks like a fit.

See the work before you put it in a bid.

Explore an example feasibility intelligence report first, live link and PDF, and judge the output before spending time on a call. When you are ready, bring us a trial you have already delivered and see whether the read matches the enrolment you actually saw.

See an example report Book a walkthrough